Sample Set Annotation Tool: Expression data from monocytes and monocyte derived macrophages-GSE52647

Study Design
Assay
Sample Info
Files
Info
Samples
Group Sets
Analysis

Purpose

Macrophages play a key role in both innate and adaptive immunity, but our knowledge on the changes in transcription regulation that occurs during their differentiation from monocytes is still limited. In this study, we used a meta-analysis followed by a systems biology approach for the identification of differentially expressed genes between monocytes and macrophages and possible regulators of these changes in transcription.

Hypothesis

Experimental Design

Monocytes isolated from human peripherial mononuclear cells were differentiated in monocyte derived macrophages by M-CSF stimulation

Experimental Variables

Controls

Methods

Additional Information

Winkler J, Fox H

Expected Samples:

12 Samples Loaded: 12

Species

Human (Homo sapiens)

Sample Source

Monocytes

Disease

Healthy

Treatment Protocol

Growth Protocol

Extraction Protocol

Storage Conditions

Sample Set Spreadsheet

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Samples Preview

Sample ID	!Sample_title	treatment	cell type	source
GSM1273533	Monocyte Donor 1	not stimulated with M-CSF	Immune cell	Human blood samples
GSM1273534	Macrophage Donor 1	stimulated with M-CSF	Immune cell	Human blood samples
GSM1273535	Monocyte Donor 2	not stimulated with M-CSF	Immune cell	Human blood samples
GSM1273536	Macrophage Donor 2	stimulated with M-CSF	Immune cell	Human blood samples
GSM1273537	Monocyte Donor 3	not stimulated with M-CSF	Immune cell	Human blood samples

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File

Samples Viewer / Editor

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Sample ID	!Sample Title	Treatment	Cell type	Source
GSM1273533	Monocyte Donor 1	not stimulated with M-CSF	Immune cell	Human blood samples
GSM1273534	Macrophage Donor 1	stimulated with M-CSF	Immune cell	Human blood samples
GSM1273535	Monocyte Donor 2	not stimulated with M-CSF	Immune cell	Human blood samples
GSM1273536	Macrophage Donor 2	stimulated with M-CSF	Immune cell	Human blood samples
GSM1273537	Monocyte Donor 3	not stimulated with M-CSF	Immune cell	Human blood samples
GSM1273538	Macrophage Donor 3	stimulated with M-CSF	Immune cell	Human blood samples
GSM1273539	Monocyte Donor 4	not stimulated with M-CSF	Immune cell	Human blood samples
GSM1273540	Macrophage Donor 4	stimulated with M-CSF	Immune cell	Human blood samples
GSM1273541	Monocyte Donor 5	not stimulated with M-CSF	Immune cell	Human blood samples
GSM1273542	Macrophage Donor 5	stimulated with M-CSF	Immune cell	Human blood samples
GSM1273543	Monocyte Donor 6	not stimulated with M-CSF	Immune cell	Human blood samples
GSM1273544	Macrophage Donor 6	stimulated with M-CSF	Immune cell	Human blood samples

Group Sets View in Gene Expression Browser

Name
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Treatment	Default	View
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Module Analysis

Group Set
All Samples
Treatment

SIDRA