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Clinical

Genome Wide Gene Expression Study of Circulating Monocytes in human with extremely high vs. low bone mass-GSE7158

Purpose

To search for genes functionally important for osteoclastogenesis

Hypothesis

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Experimental Design

We first recruited 878 healthy Chinese females aged 20-45 y with an average of 27.3 y when PBM is attainted and maintained. Then, we distributed the total sample according to the hip Z-score of PBM. From the bottom 100 and top 100 subjects of the PBM phenotypic distribution, we selected 12 subjects (Low-PBM 1-12) and 14 (High-PBM 1-14) with extremely low and high PBM for further DNA microarray experiments.Total RNA was extracted from monocytes

Experimental Variables

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Controls

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Methods

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Additional Information

Lei S, Deng H

Microarray
Affymetrix HG-U133_Plus_2
26 Samples Loaded: 26
Human (Homo sapiens)
Monocytes
Healthy
Sample Set Spreadsheet
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Samples Preview
Sample ID !Sample_title Conditions Monocyte-Low-PBM 9 Monocyte-Low-PBM 12 Monocyte-Low-PBM 10
GSM172405 Monocyte High PBM 1 High PBM
GSM172406 Monocyte High PBM 2 High PBM
GSM172407 Monocyte High PBM 3 High PBM
GSM172408 Monocyte High PBM 4 High PBM
GSM172409 Monocyte High PBM 5 High PBM
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File
sampleset4000080_sampleannotations.csv
Sample Set Spreadsheet
Raw Signal
Raw Signal
  •   |  View in GXB »
Clinical Datasource
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Samples Viewer / Editor

All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

Sample ID !Sample Title Conditions Monocyte-Low-PBM 9 Monocyte-Low-PBM 12 Monocyte-Low-PBM 10 Monocyte-Low-PBM 11 Monocyte-Low-PBM 1 Monocyte-Low-PBM 2 Monocyte-High-PBM 14 Monocyte-Low-PBM 3 Monocyte-Low-PBM 4 Monocyte-Low-PBM 5 Monocyte-Low-PBM 6 Monocyte-Low-PBM 7 Monocyte-Low-PBM 8 Monocyte-High-PBM 7 Monocyte-High-PBM 8 Monocyte-High-PBM 5 Monocyte-High-PBM 6 Monocyte-High-PBM 10 Monocyte-High-PBM 11 Monocyte-High-PBM 12 Monocyte-High-PBM 9 Monocyte-High-PBM 13 Monocyte-High-PBM 3 Monocyte-High-PBM 4 Monocyte-High-PBM 1 Monocyte-High-PBM 2
GSM172405
Monocyte High PBM 1
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
GSM172406
Monocyte High PBM 2
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
GSM172407
Monocyte High PBM 3
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
GSM172408
Monocyte High PBM 4
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
GSM172409
Monocyte High PBM 5
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
GSM172410
Monocyte High PBM 6
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
GSM172411
Monocyte High PBM 7
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
GSM172412
Monocyte High PBM 8
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
GSM172413
Monocyte High PBM 9
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
GSM172414
Monocyte High PBM 10
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
GSM172415
Monocyte High PBM 11
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
GSM172416
Monocyte High PBM 12
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
GSM172417
Monocyte High PBM 13
High PBM
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
GSM172418
Monocyte High PBM 14
High PBM
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172419
Monocyte Low PBM 1
Low PBM
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172420
Monocyte Low PBM 2
Low PBM
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172421
Monocyte Low PBM 3
Low PBM
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172422
Monocyte Low PBM 4
Low PBM
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172423
Monocyte Low PBM 5
Low PBM
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172424
Monocyte Low PBM 6
Low PBM
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172425
Monocyte Low PBM 7
Low PBM
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172426
Monocyte Low PBM 8
Low PBM
 
 
 
 
 
 
 
 
 
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172427
Monocyte Low PBM 9
Low PBM
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172428
Monocyte Low PBM 10
Low PBM
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172429
Monocyte Low PBM 11
Low PBM
 
 
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GSM172430
Monocyte Low PBM 12
Low PBM
 
True
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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