Genome-wide analysis of lupus immune complex stimulation of purified CD14+ monocytes and how this response is regulated by C1q-GSE32278
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Total RNA was isolated from CD14+ monocytes from 2 donors after 5 hours with the following conditions: 1) Unstimulated, 2) Lupus immune complex alone, 3) Lupus immune complex + C1q, 4) C1q alone
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Santer DM, Basom R, Elkon KB
Sample ID | !Sample_title | donor | treatment | cell type |
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GSM799706 | J1 unstimulated | Donor 1 | unstimulated | CD14+ |
GSM799707 | J2 immune complex | Donor 1 | immune complex | CD14+ |
GSM799708 | J3 immune complex + C1q | Donor 1 | immune complex + C1q | CD14+ |
GSM799709 | J4 C1q alone | Donor 1 | C1q | CD14+ |
GSM799710 | L1 unstimulated | Donor 2 | unstimulated | CD14+ |
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Sample ID | !Sample Title | Donor | Treatment | Cell type |
---|---|---|---|---|
GSM799706 | J1 unstimulated |
Donor 1 |
unstimulated |
CD14+ |
GSM799707 | J2 immune complex |
Donor 1 |
immune complex |
CD14+ |
GSM799708 | J3 immune complex + C1q |
Donor 1 |
immune complex + C1q |
CD14+ |
GSM799709 | J4 C1q alone |
Donor 1 |
C1q |
CD14+ |
GSM799710 | L1 unstimulated |
Donor 2 |
unstimulated |
CD14+ |
GSM799711 | L2 immune complex |
Donor 2 |
immune complex |
CD14+ |
GSM799712 | L3 immune complex + C1q |
Donor 2 |
immune complex + C1q |
CD14+ |
GSM799713 | L4 C1q alone |
Donor 2 |
C1q |
CD14+ |
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