Sample Set Annotation Tool: Temporal transcriptional changes in human monocytes following acute myocardial infarction: The GerMIFs monocyte expression study-GSE28454

Study Design
Assay
Sample Info
Files
Info
Samples
Group Sets
Analysis

Purpose

Hypothesis

Experimental Design

Monocytes play a central role in the inflammatory response that follows acute myocardial infarction (MI). In order to study phenotypic adaptation of this cell type, we investigated patterns of monocyte gene expression in circulating monocytes at various stages of MI. Circulating monocytes were isolated from venous blood of MI patients at three time points: t1: within 6 hours after onset of chest pain (acute phase), t2: 3 days after MI (subacute phase), t3: 90 days after MI (chronic phase). For comparison, we studied a control group (n=21, data to be submitted later) with stable coronary artery disease. Illumina Ref-8 v3.0 microarray arrays were used for whole-genome transcriptional profiling.

Experimental Variables

Controls

Methods

Additional Information

Maouche S, Sager HB, Aherrahrou Z, Belz S, Brocheton J, Proust C, Tennstedt S, Ammerlahn H, Riedel C, Stritzke J, Kurowski V, Rice KM, Goodall AH,Hengstenberg C, Ouwehand WH, Samani NJ, Cambien F, Erdmann J,Schunkert1 H, Diemert Pclick here to enter text

Expected Samples:

76 Samples Loaded: 76

Species

Human (Homo sapiens)

Sample Source

Monocytes

Disease

Acute Myocardial Infarction

Treatment Protocol

Growth Protocol

Extraction Protocol

Storage Conditions

Sample Set Spreadsheet

Please log in in order to upload files.

Samples Preview

Sample ID	Age	Gender	!Sample_title	cell type	stage of mi infection
GSM703192	53	male	Monocyte RNA 6h X4300799014_C_t1	monocyte	6h
GSM703193	43	male	Monocyte RNA 6h X4300799014_E_t1	monocyte	6h
GSM703194	71	male	Monocyte RNA 6h X4300799014_G_t1	monocyte	6h
GSM703195	63	Female	Monocyte RNA 6h X4300799015_E_t1	monocyte	6h
GSM703196	80	male	Monocyte RNA 6h X4300799018_B_t1	monocyte	6h

Please log in in order to upload files.

File

Samples Viewer / Editor

All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

Sample ID	Age	Gender	!Sample Title	Cell type	Stage of mi infection
GSM703192	53	male	Monocyte RNA 6h X4300799014_C_t1	monocyte	6h
GSM703193	43	male	Monocyte RNA 6h X4300799014_E_t1	monocyte	6h
GSM703194	71	male	Monocyte RNA 6h X4300799014_G_t1	monocyte	6h
GSM703195	63	Female	Monocyte RNA 6h X4300799015_E_t1	monocyte	6h
GSM703196	80	male	Monocyte RNA 6h X4300799018_B_t1	monocyte	6h
GSM703197	55	male	Monocyte RNA 6h X4300799018_F_t1	monocyte	6h
GSM703198	66	male	Monocyte RNA 6h X4300799018_H_t1	monocyte	6h
GSM703199	54	male	Monocyte RNA 6h X4300799020_A_t1	monocyte	6h
GSM703200	58	male	Monocyte RNA 6h X4300799020_C_t1	monocyte	6h
GSM703201	30	male	Monocyte RNA 6h X4300799030_B_t1	monocyte	6h
GSM703202	59	Female	Monocyte RNA 6h X4300799030_C_t1	monocyte	6h
GSM703203	72	male	Monocyte RNA 6h X4300799030_D_t1	monocyte	6h
GSM703204	54	male	Monocyte RNA 6h X4300799030_E_t1	monocyte	6h
GSM703205	64	male	Monocyte RNA 6h X4300799030_F_t1	monocyte	6h
GSM703206	72	Female	Monocyte RNA 6h X4300799030_G_t1	monocyte	6h
GSM703207	67	male	Monocyte RNA 6h X4311471114_A_t1	monocyte	6h
GSM703208	69	male	Monocyte RNA 6h X4311471114_B_t1	monocyte	6h
GSM703209	65	Female	Monocyte RNA 6h X4311471114_C_t1	monocyte	6h
GSM703210	48	male	Monocyte RNA 6h X4311471114_E_t1	monocyte	6h
GSM703211	42	male	Monocyte RNA 6h X4311471114_G_t1	monocyte	6h
GSM703212	45	male	Monocyte RNA 6h X4311471115_A_t1	monocyte	6h
GSM703213	54	Female	Monocyte RNA 6h X4311471115_C_t1	monocyte	6h
GSM703214	58	Female	Monocyte RNA 6h X4311471115_E_t1	monocyte	6h
GSM703215	62	male	Monocyte RNA 6h X4311471115_G_t1	monocyte	6h
GSM703216	65	Female	Monocyte RNA 6h X4311471116_C_t1	monocyte	6h
GSM703217	57	male	Monocyte RNA 6h X4311471116_E_t1	monocyte	6h
GSM703218	53	male	Monocyte RNA 72h X4300799014_D_t3	monocyte	72h
GSM703219	43	male	Monocyte RNA 72h X4300799014_F_t3	monocyte	72h
GSM703220	71	male	Monocyte RNA 72h X4300799014_H_t3	monocyte	72h
GSM703221	30	male	Monocyte RNA 72h X4300799015_A_t3	monocyte	72h
GSM703222	59	Female	Monocyte RNA 72h X4300799015_B_t3	monocyte	72h
GSM703223	72	male	Monocyte RNA 72h X4300799015_C_t3	monocyte	72h
GSM703224	54	male	Monocyte RNA 72h X4300799015_D_t3	monocyte	72h
GSM703225	63	Female	Monocyte RNA 72h X4300799015_F_t3	monocyte	72h
GSM703226	64	male	Monocyte RNA 72h X4300799015_G_t3	monocyte	72h
GSM703227	80	Female	Monocyte RNA 72h X4300799015_H_t3	monocyte	72h
GSM703228	67	male	Monocyte RNA 72h X4300799018_A_t3	monocyte	72h
GSM703229	80	male	Monocyte RNA 72h X4300799018_C_t3	monocyte	72h
GSM703230	69	male	Monocyte RNA 72h X4300799018_D_t3	monocyte	72h
GSM703231	65	Female	Monocyte RNA 72h X4300799018_E_t3	monocyte	72h
GSM703232	55	male	Monocyte RNA 72h X4300799018_G_t3	monocyte	72h
GSM703233	54	male	Monocyte RNA 72h X4300799020_B_t3	monocyte	72h
GSM703234	58	male	Monocyte RNA 72h X4300799030_A_t3	monocyte	72h
GSM703235	72	Female	Monocyte RNA 72h X4300799030_H_t3	monocyte	72h
GSM703236	57	male	Monocyte RNA 72h X4300799032_A_t3	monocyte	72h
GSM703237	66	male	Monocyte RNA 72h X4311471114_D_t3	monocyte	72h
GSM703238	48	male	Monocyte RNA 72h X4311471114_F_t3	monocyte	72h
GSM703239	42	male	Monocyte RNA 72h X4311471114_H_t3	monocyte	72h
GSM703240	45	male	Monocyte RNA 72h X4311471115_B_t3	monocyte	72h
GSM703241	54	Female	Monocyte RNA 72h X4311471115_D_t3	monocyte	72h
GSM703242	58	Female	Monocyte RNA 72h X4311471115_F_t3	monocyte	72h
GSM703243	62	male	Monocyte RNA 72h X4311471115_H_t3	monocyte	72h
GSM703244	62	male	Monocyte RNA 72h X4311471116_B_t3	monocyte	72h
GSM703245	65	Female	Monocyte RNA 72h X4311471116_D_t3	monocyte	72h
GSM703246	66	male	Monocyte RNA 90 days X4559291046_A_t90	monocyte	90d
GSM703247	62	male	Monocyte RNA 90 days X4559291046_B_t90	monocyte	90d
GSM703248	43	male	Monocyte RNA 90 days X4559291046_C_t90	monocyte	90d
GSM703249	42	male	Monocyte RNA 90 days X4559291046_D_t90	monocyte	90d
GSM703250	45	male	Monocyte RNA 90 days X4559291046_E_t90	monocyte	90d
GSM703251	62	male	Monocyte RNA 90 days X4559291046_F_t90	monocyte	90d
GSM703252	58	male	Monocyte RNA 90 days X4561606068_A_t90	monocyte	90d
GSM703253	30	male	Monocyte RNA 90 days X4561606068_B_t90	monocyte	90d
GSM703254	72	Female	Monocyte RNA 90 days X4561606068_C_t90	monocyte	90d
GSM703255	55	male	Monocyte RNA 90 days X4561606068_D_t90	monocyte	90d
GSM703256	48	male	Monocyte RNA 90 days X4561606068_E_t90	monocyte	90d
GSM703257	54	Female	Monocyte RNA 90 days X4561606068_F_t90	monocyte	90d
GSM703258	58	Female	Monocyte RNA 90 days X4561606068_G_t90	monocyte	90d
GSM703259	57	male	Monocyte RNA 90 days X4561606068_H_t90	monocyte	90d
GSM703260	80	male	Monocyte RNA 90 days X4561606069_A_t90	monocyte	90d
GSM703261	54	male	Monocyte RNA 90 days X4561606069_B_t90	monocyte	90d
GSM703262	54	male	Monocyte RNA 90 days X4561606069_C_t90	monocyte	90d
GSM703263	53	male	Monocyte RNA 90 days X4561606069_D_t90	monocyte	90d
GSM703264	71	male	Monocyte RNA 90 days X4561606069_E_t90	monocyte	90d
GSM703265	64	male	Monocyte RNA 90 days X4561606069_F_t90	monocyte	90d
GSM703266	67	male	Monocyte RNA 90 days X4561606069_G_t90	monocyte	90d
GSM703267	69	male	Monocyte RNA 90 days X4561606069_H_t90	monocyte	90d

Group Sets View in Gene Expression Browser

Name
All Samples		View
State of MI infection	Default	View
In order to make new Group Sets or change settings, please log in.

Module Analysis

Group Set
All Samples
State of MI infection

SIDRA