cMyb and vMyb in human monocytes-GSE2816
The transcriptional activities of c-Myb and its oncogenic variant v-Myb were compared by expressing them in primary human monocytes using recombinant adenovirus vectors. All the samples were compared to cells infected with a control adenovirus expressing only GFP. The results showed that v-Myb, which differs from c-Myb only by N- and C-terminal deletions and eleven amino acid substitutions, has a qualitatively different transcriptional activity.
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2 replicates of each type were analyzed. Replicates were performed independently, more than a week apart.
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Sample ID | !Sample_title | treatment | Monocytes from buffy coat preparation |
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GSM60924 | control virus-infected replicate 1 (monocytes) | Control | True |
GSM60925 | control virus-infected replicate 2 (monocytes) | Control | True |
GSM60926 | cMyb virus-infected replicate 1 (monocytes) | cMyb | True |
GSM60927 | cMyb virus-infected replicate 2 (monocytes) | cMyb | True |
GSM60928 | vMyb virus-infected replicate 1 (monocytes) | vMyb | True |
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Sample ID | !Sample Title | Treatment | Monocytes from buffy coat preparation |
---|---|---|---|
GSM60924 | control virus-infected replicate 1 (monocytes) |
Control |
True |
GSM60925 | control virus-infected replicate 2 (monocytes) |
Control |
True |
GSM60926 | cMyb virus-infected replicate 1 (monocytes) |
cMyb |
True |
GSM60927 | cMyb virus-infected replicate 2 (monocytes) |
cMyb |
True |
GSM60928 | vMyb virus-infected replicate 1 (monocytes) |
vMyb |
True |
GSM60929 | vMyb virus-infected replicate 2 (monocytes) |
vMyb |
True |
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