Inflammatory Expression Profiles in Monocyte to Macrophage Differentiation amongst Patients with Systemic Lupus Erythematosus and Healthy Controls with and without an Atherosclerosis Phenotype-GSE37356
To examine mononuclear cell gene expression profiles in patients with and without SLE and subsets with and without atherosclerosis
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Monocytes were obtained from 20 patients with SLE and 16 healthy controls and were in vitro differentiated into macrophages. Subjects also underwent laboratory and imaging studies of the coronary arteries, carotid arteries, and aorta to evaluate for subclinical atherosclerosis.
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Ramsey-Goldman R, Korman B
| Sample ID | !Sample_title | cell type | tissue | atherosclerosis status | lupus status |
|---|---|---|---|---|---|
| GSM916575 | L30c mono | monocyte | blood | no | control |
| GSM916576 | L30c Mac-MCSF | macrophage | blood | no | control |
| GSM916577 | L35c mono (1) | monocyte | blood | yes | control |
| GSM916578 | L45 mono | monocyte | blood | no | case |
| GSM916579 | L45 Mac-MCSF | macrophage | blood | no | case |
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| Sample ID | !Sample Title | Cell type | Tissue | Atherosclerosis status | Lupus status | Sample conditions |
|---|---|---|---|---|---|---|
| GSM916575 | L30c mono |
monocyte |
blood |
no |
control |
H_Mono |
| GSM916576 | L30c Mac-MCSF |
macrophage |
blood |
no |
control |
H_Mac |
| GSM916577 | L35c mono (1) |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916578 | L45 mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916579 | L45 Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916580 | L46c mono |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916581 | L46c Mac-MCSF |
macrophage |
blood |
yes |
control |
H_Mac |
| GSM916582 | L69 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916583 | L95R Mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916584 | L95R Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916585 | L124 Mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916586 | L124 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916587 | L9 mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916588 | L9 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916589 | L28 mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916590 | L28 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916591 | L38c mono |
monocyte |
blood |
no |
control |
H_Mono |
| GSM916592 | L38c Mac-MCSF |
macrophage |
blood |
no |
control |
H_Mac |
| GSM916593 | L70 mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916594 | L70 Mac |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916595 | L56c mono |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916596 | L56c Mac-MCSF |
macrophage |
blood |
yes |
control |
H_Mac |
| GSM916597 | L112 Mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916598 | L112 Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916599 | L51c mono |
monocyte |
blood |
no |
control |
H_Mono |
| GSM916600 | L51c Mac-MCSF |
macrophage |
blood |
no |
control |
H_Mac |
| GSM916601 | L52 mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916602 | L52 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916603 | L60 mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916604 | L60 Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916605 | L76c Mono |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916606 | L76c Mac-MCSF |
macrophage |
blood |
yes |
control |
H_Mac |
| GSM916607 | L128 Mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916608 | L128 Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916609 | L172 Mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916610 | L172 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916611 | L8 Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916612 | L35c Mac-MCSF (1) |
macrophage |
blood |
yes |
control |
H_Mac |
| GSM916613 | L40 mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916614 | L40 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916615 | L81c Mono |
monocyte |
blood |
no |
control |
H_Mono |
| GSM916616 | L81c Mac-MCSF |
macrophage |
blood |
no |
control |
H_Mac |
| GSM916617 | L106c Mono |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916618 | L106c Mac-MCSF |
macrophage |
blood |
yes |
control |
H_Mac |
| GSM916619 | L130 Mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916620 | L130 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916621 | L153 Mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916622 | L153 Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916623 | L35c mono (2) |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916624 | L35c Mac-MCSF (2) |
macrophage |
blood |
yes |
control |
H_Mac |
| GSM916625 | L49 Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916626 | L49 mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916627 | L64c mono |
monocyte |
blood |
no |
control |
H_Mono |
| GSM916628 | L64c Mac-MCSF |
macrophage |
blood |
no |
control |
H_Mac |
| GSM916629 | L114c Mono |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916630 | L114c Mac-MCSF |
macrophage |
blood |
yes |
control |
H_Mac |
| GSM916631 | L164c Mono |
monocyte |
blood |
no |
control |
H_Mono |
| GSM916632 | L164c Mac-MCSF |
macrophage |
blood |
no |
control |
H_Mac |
| GSM916633 | L199 Mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916634 | L199 Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916635 | L8 mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916636 | L54c mono |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916637 | L54c Mac-MCSF |
macrophage |
blood |
yes |
control |
H_Mac |
| GSM916638 | L69 Mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916639 | L72 Mono |
monocyte |
blood |
no |
case |
SLE_Mono |
| GSM916640 | L72 Mac-MCSF |
macrophage |
blood |
no |
case |
SLE_Mac |
| GSM916641 | L75c Mono |
monocyte |
blood |
no |
control |
H_Mono |
| GSM916642 | L75c Mac-MCSF |
macrophage |
blood |
no |
control |
H_Mac |
| GSM916643 | L149R Mono |
monocyte |
blood |
yes |
case |
SLE_Mono |
| GSM916644 | L149R Mac-MCSF |
macrophage |
blood |
yes |
case |
SLE_Mac |
| GSM916645 | L165c Mono |
monocyte |
blood |
yes |
control |
H_Mono |
| GSM916646 | L165c Mac-MCSF |
macrophage |
blood |
yes |
control |
H_Mac |
| Name | ||
|---|---|---|
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