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Clinical

Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells-GSE72642

Purpose

To demonstrate the potential use of such cell subtype-specific genomic expression data, a number of the major genes previously reported to be regulated in ischemic stroke, migraine, and Tourette syndrome are shown to be associated with distinct cell populations in blood.

Hypothesis

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Experimental Design

This study includes data from major blood cell types from normal individuals. These cell types include CD4+ T cells, CD8+ T cells, CD19+ B cells, CD56+ natural killer cells, CD14+ monocytes and PMN (polymorphonuclear cells). The data were hybridized on 3 separate batches of gene chips.

Experimental Variables

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Controls

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Methods

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Additional Information
  • Du X, Tang Y, Xu H, Lit L et al. Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome. Genomics2006 Jun;87(6):693-703. PMID: 16546348
  • Microarray
    Affymetrix HG-U133_Plus_2
    18 Samples Loaded: 18
    Human (Homo sapiens)
    Neutrophils , Monocytes , T cells , NK Cells , B cells
    Healthy
    Sample Set Spreadsheet
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    Samples Preview
    Sample ID !Sample_title cell type tissue diagnosis
    GSM1867065 peripheral blood CD19+ B cells, replicate 1 CD19+ B cells peripheral blood healthy
    GSM1867066 peripheral blood CD4+ T cells, replicate 1 CD4+ T cells peripheral blood healthy
    GSM1867067 peripheral blood CD8+ T cells, replicate 1 CD8+ T cells peripheral blood healthy
    GSM1867068 peripheral blood CD14+ monocytes, replicate 1 CD14+ monocytes peripheral blood healthy
    GSM1867069 peripheral blood CD56+ NK cells, replicate 1 CD56+ NK cells peripheral blood healthy
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    File
    Log2 Transformed
    Raw Signal
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    Clinical Datasource
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    Samples Viewer / Editor

    All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

    Sample ID !Sample Title Cell type Tissue Diagnosis
    GSM1867065
    peripheral blood CD19+ B cells, replicate 1
    CD19+ B cells
    peripheral blood
    healthy
    GSM1867066
    peripheral blood CD4+ T cells, replicate 1
    CD4+ T cells
    peripheral blood
    healthy
    GSM1867067
    peripheral blood CD8+ T cells, replicate 1
    CD8+ T cells
    peripheral blood
    healthy
    GSM1867068
    peripheral blood CD14+ monocytes, replicate 1
    CD14+ monocytes
    peripheral blood
    healthy
    GSM1867069
    peripheral blood CD56+ NK cells, replicate 1
    CD56+ NK cells
    peripheral blood
    healthy
    GSM1867070
    peripheral blood PMN, replicate 1
    polymorphonuclear cells
    peripheral blood
    healthy
    GSM1867071
    peripheral blood CD19+ B cells, replicate 2
    CD19+ B cells
    peripheral blood
    healthy
    GSM1867072
    peripheral blood CD4+ T cells, replicate 2
    CD4+ T cells
    peripheral blood
    healthy
    GSM1867073
    peripheral blood CD8+ T cells, replicate 2
    CD8+ T cells
    peripheral blood
    healthy
    GSM1867074
    peripheral blood CD14+ monocytes, replicate 2
    CD14+ monocytes
    peripheral blood
    healthy
    GSM1867075
    peripheral blood CD56+ NK cells, replicate 2
    CD56+ NK cells
    peripheral blood
    healthy
    GSM1867076
    peripheral blood PMN, replicate 2
    polymorphonuclear cells
    peripheral blood
    healthy
    GSM1867077
    peripheral blood CD19+ B cells, replicate 3
    CD19+ B cells
    peripheral blood
    healthy
    GSM1867078
    peripheral blood CD4+ T cells, replicate 3
    CD4+ T cells
    peripheral blood
    healthy
    GSM1867079
    peripheral blood CD8+ T cells, replicate 3
    CD8+ T cells
    peripheral blood
    healthy
    GSM1867080
    peripheral blood CD14+ monocytes, replicate 3
    CD14+ monocytes
    peripheral blood
    healthy
    GSM1867081
    peripheral blood CD56+ NK cells, replicate 3
    CD56+ NK cells
    peripheral blood
    healthy
    GSM1867082
    peripheral blood PMN, replicate 3
    polymorphonuclear cells
    peripheral blood
    healthy

    Group Sets View in Gene Expression Browser

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