Sample Set Annotation Tool: Comparison study between Uremic patient with Healthy control-GSE43484

Study Design
Assay
Sample Info
Files
Info
Samples
Group Sets
Analysis

Purpose

To explore the gene expression profile and to identify differences in activated pathways in monocytes relevant to the pathophysiology of atherosclerosis and increased susceptibility to infections.

Hypothesis

Experimental Design

Monocytes from CKD patients (stages 4 and 5, eGFR <20 ml/min x 1.73 m2) and healthy donors were collected from peripheral blood. Microarray gene expression profile was done and data were interpreted by Genespring software and Panther tools website.

Experimental Variables

Controls

Methods

Six gene expression Affymetrix chip were used. Three for each group

Additional Information

Al-Chaqmaqchi H, Moshfegh A, Dadfar E, Paulsson J, Hassan M, Jacobson SH,Lundahl J

Expected Samples:

6 Samples Loaded: 6

Species

Human (Homo sapiens)

Sample Source

Monocytes

Disease

Uremic

Treatment Protocol

Growth Protocol

Extraction Protocol

Storage Conditions

Sample Set Spreadsheet

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Samples Preview

Sample ID	!Sample_title	cell type	subject
GSM1063568	Uremic Monocyte rep1	CD14 purified perpheral blood monocytes	Uremic patient
GSM1063569	Uremic Monocyte rep2	CD14 purified perpheral blood monocytes	Uremic patient
GSM1063570	Uremic Monocyte rep3	CD14 purified perpheral blood monocytes	Uremic patient
GSM1063571	Healthy Monocyte rep1	CD14 purified perpheral blood monocytes	healthy control
GSM1063572	Healthy Monocyte rep2	CD14 purified perpheral blood monocytes	healthy control

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Sample ID	!Sample Title	Cell type	Subject
GSM1063568	Uremic Monocyte rep1	CD14 purified perpheral blood monocytes	Uremic patient
GSM1063569	Uremic Monocyte rep2	CD14 purified perpheral blood monocytes	Uremic patient
GSM1063570	Uremic Monocyte rep3	CD14 purified perpheral blood monocytes	Uremic patient
GSM1063571	Healthy Monocyte rep1	CD14 purified perpheral blood monocytes	healthy control
GSM1063572	Healthy Monocyte rep2	CD14 purified perpheral blood monocytes	healthy control
GSM1063573	Healthy Monocyte rep3	CD14 purified perpheral blood monocytes	healthy control

Group Sets View in Gene Expression Browser

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Module Analysis

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Disease status

SIDRA