Innate immune repsonses to TREM-1 activation-GSE9988
To investigate the cellular consequences of TREM-1 activation, we have characterized global gene expression changes in human monocytes in response to TREM-1 cross-linking in comparison to and combined with LPS.
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11 anonymous donors were treated with Vehicle, isotype control antibody, TREM1 antibody, LPS, isotype control antibody plus LPS and TREM1 antibody plus LPS
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Sample ID | !Sample_title | treatment | Anonymous Donor | Donor number |
---|---|---|---|---|
GSM252423 | Anti-Trem1 2 hrs Donor 1 | aTREM1 | True | Donor 1 |
GSM252424 | Anti-Trem1 2 hrs Donor 3 | aTREM1 | True | Donor 3 |
GSM252425 | Anti-Trem1 2 hrs Donor 11 | aTREM1 | True | Donor 11 |
GSM252426 | Anti-Trem1 2 hrs Donor 9 | aTREM1 | True | Donor 9 |
GSM252427 | Anti-Trem1 2 hrs Donor 5 | aTREM1 | True | Donor 5 |
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Sample ID | !Sample Title | Treatment | Anonymous Donor | Donor number |
---|---|---|---|---|
GSM252423 | Anti-Trem1 2 hrs Donor 1 |
aTREM1 |
True |
Donor 1 |
GSM252424 | Anti-Trem1 2 hrs Donor 3 |
aTREM1 |
True |
Donor 3 |
GSM252425 | Anti-Trem1 2 hrs Donor 11 |
aTREM1 |
True |
Donor 11 |
GSM252426 | Anti-Trem1 2 hrs Donor 9 |
aTREM1 |
True |
Donor 9 |
GSM252427 | Anti-Trem1 2 hrs Donor 5 |
aTREM1 |
True |
Donor 5 |
GSM252428 | Anti-Trem1 2 hrs Donor 10 |
aTREM1 |
True |
Donor 10 |
GSM252429 | Anti-Trem1 2 hrs Donor 2 |
aTREM1 |
True |
Donor 2 |
GSM252430 | Anti-Trem1 2 hrs Donor 7 |
aTREM1 |
True |
Donor 7 |
GSM252431 | Anti-Trem1 2 hrs Donor 6 |
aTREM1 |
True |
Donor 6 |
GSM252432 | Anti-Trem1 2 hrs Donor 4 |
aTREM1 |
True |
Donor 4 |
GSM252433 | Anti-Trem1 2 hrs Donor 8 |
aTREM1 |
True |
Donor 8 |
GSM252434 | Control/LPS 2 hrs Donor 9 |
LPS Control |
True |
Donor 9 |
GSM252435 | Control/LPS 2 hrs Donor 5 |
LPS Control |
True |
Donor 5 |
GSM252436 | Control/LPS 2 hrs Donor 4 |
LPS Control |
True |
Donor 4 |
GSM252437 | Control/LPS 2 hrs Donor 10 |
LPS Control |
True |
Donor 10 |
GSM252438 | Control/LPS 2 hrs Donor 8 |
LPS Control |
True |
Donor 8 |
GSM252439 | Control/LPS 2 hrs Donor 7 |
LPS Control |
True |
Donor 7 |
GSM252440 | Control/LPS 2 hrs Donor 2 |
LPS Control |
True |
Donor 2 |
GSM252441 | Control/LPS 2 hrs Donor 3 |
LPS Control |
True |
Donor 3 |
GSM252442 | Control/LPS 2 hrs Donor 6 |
LPS Control |
True |
Donor 6 |
GSM252443 | LPS Low 2 hrs Donor 7 |
Low LPS |
True |
Donor 7 |
GSM252444 | LPS Low 2 hrs Donor 4 |
Low LPS |
True |
Donor 4 |
GSM252445 | LPS Low 2 hrs Donor 10 |
Low LPS |
True |
Donor 10 |
GSM252447 | LPS Low 2 hrs Donor 3 |
Low LPS |
True |
Donor 3 |
GSM252448 | LPS Low 2 hrs Donor 2 |
Low LPS |
True |
Donor 2 |
GSM252449 | LPS Low 2 hrs Donor 9 |
Low LPS |
True |
Donor 9 |
GSM252450 | LPS Low 2 hrs Donor 5 |
Low LPS |
True |
Donor 5 |
GSM252451 | LPS Low 2 hrs Donor 1 |
Low LPS |
True |
Donor 1 |
GSM252452 | LPS Low 2 hrs Donor 6 |
Low LPS |
True |
Donor 6 |
GSM252453 | LPS Low 2 hrs Donor 11 |
Low LPS |
True |
Donor 11 |
GSM252454 | LPS Low 2 hrs Donor 8 |
Low LPS |
True |
Donor 8 |
GSM252455 | Anti-Trem1/LPS 2 hrs Donor 4 |
aTREM1+LPS |
True |
Donor 4 |
GSM252456 | Anti-Trem1/LPS 2 hrs Donor 9 |
aTREM1+LPS |
True |
Donor 9 |
GSM252457 | Anti-Trem1/LPS 2 hrs Donor 7 |
aTREM1+LPS |
True |
Donor 7 |
GSM252458 | Anti-Trem1/LPS 2 hrs Donor 5 |
aTREM1+LPS |
True |
Donor 5 |
GSM252459 | Anti-Trem1/LPS 2 hrs Donor 11 |
aTREM1+LPS |
True |
Donor 11 |
GSM252460 | Anti-Trem1/LPS 2 hrs Donor 6 |
aTREM1+LPS |
True |
Donor 6 |
GSM252461 | Anti-Trem1/LPS 2 hrs Donor 3 |
aTREM1+LPS |
True |
Donor 3 |
GSM252462 | Anti-Trem1/LPS 2 hrs Donor 10 |
aTREM1+LPS |
True |
Donor 10 |
GSM252463 | Anti-Trem1/LPS 2 hrs Donor 2 |
aTREM1+LPS |
True |
Donor 2 |
GSM252464 | Anti-Trem1/LPS 2 hrs Donor 1 |
aTREM1+LPS |
True |
Donor 1 |
GSM252465 | Control 2 hrs Donor 6 |
Control |
True |
Donor 6 |
GSM252466 | Control 2 hrs Donor 2 |
Control |
True |
Donor 2 |
GSM252467 | Control 2 hrs Donor 11 |
Control |
True |
Donor 11 |
GSM252468 | Control 2 hrs Donor 9 |
Control |
True |
Donor 9 |
GSM252469 | Control 2 hrs Donor 3 |
Control |
True |
Donor 3 |
GSM252470 | Control 2 hrs Donor 10 |
Control |
True |
Donor 10 |
GSM252471 | Control 2 hrs Donor 5 |
Control |
True |
Donor 5 |
GSM252472 | Control 2 hrs Donor 1 |
Control |
True |
Donor 1 |
GSM252473 | Control 2 hrs Donor 8 |
Control |
True |
Donor 8 |
GSM252474 | Control 2 hrs Donor 7 |
Control |
True |
Donor 7 |
GSM252475 | Control 2 hrs Donor 4 |
Control |
True |
Donor 4 |
GSM252476 | Vehicle 2 hrs Donor 11 |
Vehicle |
True |
Donor 11 |
GSM252477 | Vehicle 2 hrs Donor 8 |
Vehicle |
True |
Donor 8 |
GSM252478 | Vehicle 2 hrs Donor 6 |
Vehicle |
True |
Donor 6 |
GSM252479 | Vehicle 2 hrs Donor 4 |
Vehicle |
True |
Donor 4 |
GSM252480 | Vehicle 2 hrs Donor 3 |
Vehicle |
True |
Donor 3 |
GSM252481 | Vehicle 2 hrs Donor 2 |
Vehicle |
True |
Donor 2 |
GSM252482 | Vehicle 2 hrs Donor 5 |
Vehicle |
True |
Donor 5 |
GSM252483 | Vehicle 2 hrs Donor 7 |
Vehicle |
True |
Donor 7 |
GSM252484 | Vehicle 2 hrs Donor 9 |
Vehicle |
True |
Donor 9 |
GSM252485 | Vehicle 2 hrs Donor 1 |
Vehicle |
True |
Donor 1 |
Name | ||
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