Expression data from monocytes and monocyte derived macrophages-GSE52647
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| Description | Expression data from monocytes and monocyte derived macrophages-GSE52647 |
| Purpose | Macrophages play a key role in both innate and adaptive immunity, but our knowledge on the changes in transcription regulation that occurs during their differentiation from monocytes is still limited. In this study, we used a meta-analysis followed by a systems biology approach for the identification of differentially expressed genes between monocytes and macrophages and possible regulators of these changes in transcription. |
| Experimental Design | Monocytes isolated from human peripherial mononuclear cells were differentiated in monocyte derived macrophages by M-CSF stimulation |
| Additional Information | Winkler J, Fox H |
| Platform | Affymetrix HuGene 1.0 ST v1 |
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