Transcriptome analysis of HIV-infected peripheral blood monocytes-GSE50011
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| Description | Transcriptome analysis of HIV-infected peripheral blood monocytes-GSE50011 |
| Hypothesis | Transcriptome changes in peripheral blood monocytes relate to neurocognitive functioning in HIV+ individuals, and that such alterations could be useful as biomarkers of worsening HIV-associated neurocognitive disorder (HAND). |
| Experimental Design | mRNA was isolated from the monocytes of 86 HIV+ adults and analyzed with the Illumina HT-12 v4 Expression BeadChip. Neurocognitive functioning, HAND diagnosis, and other clinical and virologic variables were determined. |
| Methods | mRNA was isolated from the monocytes of 86 HIV+ adults and analyzed with the Illumina HT-12 v4 Expression BeadChip. Neurocognitive functioning, HAND diagnosis, and other clinical and virologic variables were determined. |
| Additional Information | |
| Platform | Illumina HumanHT-12 v4 |
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