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SIDRA

GXB

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Description

Peripheral Blood Monocyte Gene Expression in Recent-Onset Type 1 Diabetes-GSE33440

Purpose

Novel biomarkers of disease progression after type 1 diabetes onset are needed.

Experimental Design

CD14+ monocytes from a total of 16 children with recent-onset type 1 diabetes and 6 adult healthy controls were profiled in 2 independent microarrays.

Methods

We profiled peripheral blood (PB) monocyte gene expression in 6 healthy subjects and 16 children with type 1 diabetes diagnosed ~3 months previously, and analyzed clinical features from diagnosis to 1 year.

Additional Information
  • Irvine KM, Gallego P, An X, Best SE et al. Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes. Diabetes 2012 May;61(5):1281-90. PMID: 22403299
  • Platform Illumina HumanHT-12 v3
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