Description | cMyb and vMyb in human monocytes-GSE2816 |
Purpose | The transcriptional activities of c-Myb and its oncogenic variant v-Myb were compared by expressing them in primary human monocytes using recombinant adenovirus vectors. All the samples were compared to cells infected with a control adenovirus expressing only GFP. The results showed that v-Myb, which differs from c-Myb only by N- and C-terminal deletions and eleven amino acid substitutions, has a qualitatively different transcriptional activity. |
Experimental Design | 2 replicates of each type were analyzed. Replicates were performed independently, more than a week apart. |
Additional Information | |
Platform | Affymetrix HG-U133_Plus_2 |
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