Description | Genome-wide analysis of monocytes and T cells' response to interferon beta-GSE34627 |
Purpose | To characterized the IFN-? transcriptional response in monocytes, a small but influential cell-subset, using gene expression profile and pathway analysis. |
Hypothesis | The unique expression profile of monocytes in response to Interferon-beta (IFN-?) might be masked by the response profile of the more abundant T cells. |
Experimental Design | Monocytes and T lymphocytes were isolated from 3 healthy volunteers. For each sample the expression profile of untreated cells was compared to the profile of IFN-? treated cells, i.e. 4 samples from each donor (2 cell types, with and without treatment), 12 samples total. |
Additional Information | |
Platform | Illumina HumanWG-6 v3 |
(Uploaded through the Files tab in the Annotation Tool)
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