GXB: Innate immune repsonses to TREM-1 activation-GSE9988

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Innate immune repsonses to TREM-1 activation-GSE9988

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Description	Innate immune repsonses to TREM-1 activation-GSE9988
Purpose	To investigate the cellular consequences of TREM-1 activation, we have characterized global gene expression changes in human monocytes in response to TREM-1 cross-linking in comparison to and combined with LPS.
Experimental Design	11 anonymous donors were treated with Vehicle, isotype control antibody, TREM1 antibody, LPS, isotype control antibody plus LPS and TREM1 antibody plus LPS
Additional Information	Dower K, Ellis DK, Saraf K, Jelinsky SA et al. Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide. J Immunol 2008 Mar 1;180(5):3520-34. PMID: 18292579
Platform	Affymetrix HG-U133_Plus_2

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