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SIDRA

GXB

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Description

Interleukin-1- and Type I Interferon-Dependent Enhanced Immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef Vaccine Vector with Dual Deletions of Type I and Type II Interferon-Binding Proteins-GSE65412

Experimental Design

Primary Human monocytes from 5 donors were incubated with each following vectors nyvacdb, nyvadb19r, nyvaccdb8rb19r_6h, untreated control and collected at 6h.

Methods

Primary monocytes

Additional Information
  • Delaloye J, Filali-Mouhim A, Cameron MJ, Haddad EK et al. Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins. J Virol 2015 Apr;89(7):3819-32. PMID: 25609807
  • Platform Illumina HumanHT-12 v4
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