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SIDRA

GXB

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Description

Transcriptome analysis of primary monocytes from HIV+ patients with differential responses to therapy-GSE52900

Purpose

This study aimed at investigating the monocytic transcriptome distinction between patients with sustained virus suppression (BDL) and patients with virological failure during highly active antiretroviral therapy (HAART).

Experimental Design

Total RNA obtained from primary monocytes from five HIV+ patients on HAART who sustainably controlled HIV below detection level (BDL), five HIV+ patients on HAART who consecutively experienced viremia and four healthy HIV sero-negative controls were compared against each other.

Additional Information
  • Wu JQ, Sassé TR, Saksena MM, Saksena NK. Transcriptome analysis of primary monocytes from HIV-positive patients with differential responses to antiretroviral therapy. Virol J 2013 Dec 27;10:361. PMID: 24370116
  • Platform Illumina HumanHT-12 v3
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