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SIDRA

GXB

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Description

Treatment of human monocytes with TLR7 or TLR8 agonists-GSE64480

Purpose

Goal was to detect differences in response to TLR7 versus TLR8 agonists in human monocytes from healthy donors

Experimental Design

3 deidentified donors from the Red Cross, monocytes from each donor incubated overnight with either vehicle, TLR7 agonist or TLR8 agonist

Additional Information
  • Elavazhagan S, Fatehchand K, Santhanam V, Fang H et al. Granzyme B expression is enhanced in human monocytes by TLR8 agonists and contributes to antibody-dependent cellular cytotoxicity. J Immunol 2015 Mar 15;194(6):2786-95. PMID: 25667415
  • Platform Affymetrix HG-U133_Plus_2
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