Bacillus anthracis' lethal toxin induces broad transcriptional responses in human peripheral monocyte-GSE34407 (Affymetrix: HG-U133_Plus_2)
Human monocyte activation with NOD2L vs. TLR2/1L-GSE34156 (Affymetrix: HG-U133_Plus_2)
Peripheral Blood Monocyte Gene Expression in Recent-Onset Type 1 Diabetes-GSE33440 (Illumina: HT12 V3)
CD4 on human monocytes -GSE32939 (Affymetrix: HG-U133_Plus_2)
Transcriptome analysis of circulating monocytes in obese patients before and three months after bariatric surgery-GSE32575 (Illumina: Human_6_V2_Beta)
Genome-wide analysis of lupus immune complex stimulation of purified CD14+ monocytes and how this response is regulated by C1q-GSE32278 (Illumina: Hu V3 Ref 8)
Changes in gene expression profiles in patients with 5q- syndrome in CD14+ monocytes caused by lenalidomide treatment-GSE31460 (Illumina: Hu V3 Ref 8)
Temporal transcriptional changes in human monocytes following acute myocardial infarction: The GerMIFs monocyte expression study-GSE28454 (Illumina: Hu V3 Ref 8)
cMyb and vMyb in human monocytes-GSE2816 (Affymetrix: HG-U133_Plus_2)
Cooperative and redundant signaling of leukotriene B4 and leukotriene D4 in human monocytes-GSE24869 (Affymetrix: HG-U133_Plus_2)
Monocyte gene expression patterns distinguish subjects with and without atherosclerosis-GSE23746 (Illumina: Sentrix HuRef-8)
Monocyte vs Macrophage Study-GSE22373 (Affymetrix: HG-U133_Plus_2)
Transcriptomics of human monocytes-GSE56045 (Illumina: HT12 V4)
Cell Specific Expression in Trauma-Related Human T-Cell and Monocyte Pathways-GSE5580 (Affymetrix: HG-U133A)
Transcriptome analysis of primary monocytes from HIV+ patients with differential responses to therapy-GSE52900 (Illumina: HT12 V3)
Expression data from monocytes and monocyte derived macrophages-GSE52647 (Affymetrix: HG 1.0 ST)
Longitudinal comparison of monocytes from an HIV viremic vs avirmeic state-GSE5220 (Affymetrix: HG-U133A)
Effects of exercise on gene expression level in human monocytes-GSE51835 (Affymetrix: HG-U133_Plus_2)
Gene expression profiles in T-lymphocytes and Monocytes of participants of the Tour de France 2005-GSE5105 (Affymetrix: HG-U133_Plus_2)
Transcriptome analysis of HIV-infected peripheral blood monocytes-GSE50011 (Illumina: HT12 V4)
Transcriptome analysis of blood monocytes from sepsis patients-GSE46955 (Illumina: Human8 V2)
Gene expression profile of human monocytes stimulated with all-trans retinoic acid (ATRA) or 1,25a-dihydroxyvitamin D3 (1,25D3)-GSE46268 (Affymetrix: HG-U133_Plus_2)
Influenza virus A infected monocytes-GSE35473 (Illumina: Human V3 WG6)
Highly pathogenic influenza virus inhibit Inflammatory Responses in Monocytes via Activation of the Rar-Related Orphan Receptor Alpha (RORalpa)-GSE35283 (Affymetrix: HG-U133_Plus_2)
Genome-wide analysis of monocytes and T cells' response to interferon beta-GSE34627 (Illumina: Human V3 WG6)
Loss-of-function mutations in REP-1 affect intracellular vesicle transport in fibroblasts and monocytes of CHM patients-GSE17549 (Affymetrix: HG-U133_Plus_2)
COPD-Specific Gene Expression Signatures of Alveolar Macrophages as well as Peripheral Blood Monocytes Overlap and Correlate with Lung Function-GSE16972 (Affymetrix: HG-U133A)
Homogeneous monocytes and macrophages from hES cells following coculture-free differentiation in M-CSF and IL-3-GSE15791 (Affymetrix: HG 1.0 ST)
Quercetin supplementation and CD14+ monocyte gene expression-GSE13899 (Affymetrix: HG-U133_Plus_2)
Human blood monocyte profile in Ventilator-Associated Pneumonia patients-GSE12838 (Affymetrix: HG-U133_Plus_2)
Microarray analysis of human monocytes infected with Francisella tularensis-GSE12108 (Affymetrix: HG-U133_Plus_2)
Monocyte gene expression profiling in familial combined hyperlipidemia and its modification by atorvastatin treatment-GSE11393 (Affymetrix: HG-U133A)
Interaction of bone marrow stroma and monocytes: bone marrow stromal cell lines cultured with monocytes-GSE10595 (Affymetrix: HG-U133_Plus_2)
Gene expression profile during monocytes to macrophage differentiation-GSE8286 (Affymetrix: HG-U133A)
Leukotriene D4 induces gene expression in human monocytes through cysteinyl leukotriene type I receptor-GSE7807 (Affymetrix: HG-U133_Plus_2)
Expression data from monocytes of individuals with different collateral flow index CFI-GSE7638 (Affymetrix: HG-U133A)
Genome Wide Gene Expression Study of Circulating Monocytes in human with extremely high vs. low bone mass-GSE7158 (Affymetrix: HG-U133_Plus_2)
Effect of two weeks erythropoietin treatment on monocyte transcriptomes of cardiorenal patients-GSE17582 (Illumina: Hu V3 Ref 8)
T helper lymphocyte- and monocyte-specific type I interferon (IFN) signatures in autoimmunity and viral infection-GSE51997 (Affymetrix: HG-U133_Plus_2)
Tumor-educated circulating monocytes are powerful specific biomarkers for diagnosis of colorectal cancer-GSE47756 (Illumina: HT12 V4)
Monocytes and Dendritic cells stimulated by 13 human vaccines and LPS-GSE44721 (Illumina: HT12 V4)
Inflammatory Expression Profiles in Monocyte to Macrophage Differentiation amongst Patients with Systemic Lupus Erythematosus and Healthy Controls with and without an Atherosclerosis Phenotype-GSE37356 (Illumina: HT12 V4)
Transcriptome profiles of human monocyte and dendritic cell subsets-GSE35457 (Illumina: HT12 V4)
Gene expression profiles of human blood classical monocytes (CD14++CD16-), CD16 positive monocytes (CD14+16++ and CD14++CD16+), and CD1c+ CD19- dendritic cells-GSE34515 (Affymetrix: HG-U133_Plus_2)
Gene expression profiling of the classical (CD14++CD16-), intermediate (CD14++CD16+) and nonclassical (CD14+CD16+) human monocyte subsets-GSE25913 (Illumina: Human_6_V2_Beta)
Filaria induced monocyte dysfunction and its reversal following treatment-GSE2135 (Affymetrix: HG-U133A)
Mycobacterium tuberculosis Chaperonin 60.1 has Bipolar Effects on Human peripheral blood-derived Monocytes-GSE18794 (Affymetrix: HG 1.0 ST)
Comparison of gene expression profiles between human monocyte subsets-GSE18565 (Affymetrix: HG-U133_Plus_2)
Transcriptional profiling of CD16+ and CD16- peripheral blood monocytes from healthy individuals-GSE16836 (Affymetrix: HG-U133_Plus_2)
Treatment of human monocytes with TLR7 or TLR8 agonists-GSE64480 (Affymetrix: HG-U133_Plus_2)
GM-CSF induced gene-regulation in human monocytes-GSE63662 (Affymetrix: HG-U133_Plus_2)
Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism-GSE6054 (Affymetrix: HG-U133_Plus_2)
Human blood monocyte response to IL-17A in culture-GSE54884 (Affymetrix: HG-U133A)
Restricted Dendritic Cell and Monocyte Progenitors in Human Cord Blood and Bone Marrow-GSE65128 (Illumina: HT12 V4)
Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells-GSE72642 (Affymetrix: HG-U133_Plus_2)
Expression data from intermediate monocytes from healthy donors and autoimmune uveitis patients-GSE66936 (Affymetrix: HG-U133_Plus_2)
Comparative analysis of monocytes from healthy donors, patients with metastatic breast cancer, sepsis or tuberculosis-GSE65517 (Illumina: HT12 V4)
Gene expression data from CD14++ CD16- classical monocytes from healthy volunteers and patients with pancreatic ductal adenocarcinoma-GSE60601 (Affymetrix: HG-U133_Plus_2)
Induction of Dendritic Cell-like Phenotype in Macrophages during Foam Cell Formation-GSE7138 (Affymetrix: HG-U133A)
Divergent genome wide transcriptional profiles from immune cell subsets isolated from SLE patients with different ancestral backgrounds-GSE55447 (Illumina: HT12 V4)
Activation of the JAK/STAT pathway in Behcet’s Disease-GSE61399 (Affymetrix: HG-U133_Plus_2)
Analysis of blood myelomonocytic cells from RCC patients-GSE38424 (Illumina: HT12 V4)
Immune Variation Project (ImmVar) [CD14]-GSE56034 (Affymetrix: HG 1.0 ST)
The effect of cell subset isolation method on gene expression in leukocytes-GSE50008 (Illumina: HT12 V4)
Comparison study between Uremic patient with Healthy control-GSE43484 (Affymetrix: HG-U133A)
mRNA expression profiling of human immune cell subsets (HUG)-GSE28491 (Affymetrix: HG-U133_Plus_2)
mRNA expression profiling of human immune cell subset (Roche)-GSE28490 (Affymetrix: HG-U133_Plus_2)
Direct Cell Conversion of Human Fibroblasts to Monocytic phagocytes by Forced Expression of Monocytic Regulatory Network Elements-GSE27304 (Illumina: Human V3 WG6)
Deconvoluting Early Post-Transplant Immunity Using Purified Cell Subsets Reveals Functional Networks Not Evident by Whole Blood Analysis-GSE24223 (Affymetrix: HG-U133_Plus_2)
Ubiquinol-induced gene expression signatures are translated into reduced erythropoiesis and LDL cholesterol levels in humans-GSE21351 (Affymetrix: HG-U133_Plus_2)
Blood Transcriptional Profiles of Active TB (Separated cells)-GSE19443 (Illumina: HT12 V3)
Human monocyte and dendritic Cell Subtype Gene Arrays-GSE11943 (Affymetrix: HG-U133A)
Gene expression profiling in pediatric meningococcal sepsis reveals dynamic changes in NK-cell and cytotoxic molecules-GSE11755 (Affymetrix: HG-U133_Plus_2)
Gene Expression-Based High Throughput Screening: APL Treatment with Candidate Compounds-GSE976 (Affymetrix: HG-U133A)
Macrophage Microvesicles Induce Macrophage Differentiation and miR-223 Transfer-GSE41889 (Affymetrix: HG-U133_Plus_2)
PGE2-induced OSM expression-GSE36995 (Affymetrix: HG-U133_Plus_2)
Similarities and differences between macrophage polarized gene profiles-GSE49240 (Illumina: HT12 V4)
Nanotoxicogenomic study of ZnO and TiO2 responses-GSE39316 (Illumina: HT12 V3)
Microarray analysis of IL-10 stimulated adherent peripheral blood mononuclear cells-GSE43700 (Affymetrix: HG-U133_Plus_2)
TREM-1 is a novel therapeutic target in Psoriasis-GSE42305 (Affymetrix: HG-U133A)
New insights into key genes and pathways involved in the pathogenesis of HLA-B27-associated acute anterior uveitis-GSE37588 (Affymetrix: HG-U133_Plus_2)
Traffic-related Particulate Matter Upregulates Allergic Responses by a Notch-pathway Dependent Mechanism-GSE34025 (Affymetrix: HG-U133_Plus_2)
Subpopulations of CD163 positive macrophages are classically activated in psoriasis-GSE18686 (Illumina: HT12 V3)
Expression data from human macrophages -GSE16385 (Affymetrix: HG-U133_Plus_2)
Effects of PMN-Ectosomes on human macrophages-GSE14419 (Affymetrix: HG-U133A)
Effect of interferon-gamma on macrophage differentiation and response to Toll-like receptor ligands-GSE11864 (Affymetrix: HG-U133_Plus_2)
Performance comparison of Affymetrix and Illumina microarray technologies-GSE11430 (Affymetrix: HG-U133_Plus_2)
Innate immune repsonses to TREM-1 activation-GSE9988 (Affymetrix: HG-U133_Plus_2)
TRAIL Is a Novel Antiviral Protein against Dengue Virus-GSE9378 (Affymetrix: HG-U133A)
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response-GSE8921 (Affymetrix: HG-U133A)
Interleukin-1- and Type I Interferon-Dependent Enhanced Immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef Vaccine Vector with Dual Deletions of Type I and Type II Interferon-Binding Proteins-GSE65412 (Illumina: HT12 V4)
Effect of vitamin D treatment on human monocytes-GSE56490 (Affymetrix: HG 1.0 ST)
Alarmins MRP8 and MRP14 induce stress-tolerance in phagocytes under sterile inflammatory conditions-GSE61477 (Illumina: HT12 V4)
Blood Transcriptional Profiles in Active and Latent Tuberculosis UK (Training Set) - GSE19439 (Illumina: HT12 V3)
Bacillus anthracis' lethal toxin induces broad transcriptional responses in human peripheral monocyte-GSE34407
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Gene Symbol: CD14
Signal: --
Participant ID: --
Sample ID: --
| Description | Bacillus anthracis' lethal toxin induces broad transcriptional responses in human peripheral monocyte-GSE34407 |
| Purpose | Anthrax lethal toxin directly targets human peripheral monocytes and causes multiple aberrant gene responses that would be expected to result in defects in human monocyte’s normal signaling transduction pathways and nction. This study provides further insights into the mechanisms associated with the host immune system collapse during an anthrax infection, and suggests that anthrax LT may have additional targets outside the well-known MAPK pathway. |
| Experimental Design | There were 4 replicates, 1 control and 1 toxin treated from 4 donors, with 8 samples total. |
| Additional Information |
No information available.
| Background | Biotin | Genes001 | Genes005 | Gp95 | Housekeeping | Noise |
|---|---|---|---|---|---|---|
| -- | -- | -- | -- | -- | -- | -- |
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